Erythritol
Sugar alcohol with ~70% the sweetness of sucrose, near-zero calories. 2023 cardiovascular signal under investigation.
At a glance
How Erythritol compares to table sugar on the three numbers most people actually want.
Ten-metric breakdown
See methodology →- Taste qualityWeight 20%75
- Glycemic impactWeight 18%80
- NaturalnessWeight 10%70
- Tooth friendlinessWeight 8%90
- Overall safetyWeight 14%Pending
- Digestive comfortWeight 8%60
- Gut microbiomeWeight 8%Pending
- AftertasteWeight 6%Pending
- SustainabilityWeight 4%Pending
- Allergen safetyWeight 4%90
Source: public.sweeteners snapshot, refreshed 2026-04-27. "Pending" cells are catalogued but not yet graded by SweetSpot research.
What it actually is
Erythritol is a four-carbon sugar alcohol produced by yeast fermentation of glucose. It is 60–80% as sweet as sucrose, has near-zero calories, no glycemic effect, and is mostly absorbed in the small intestine and excreted unchanged — which is why it causes far less GI upset than other polyols.
In 2023, Hazen et al. published a Nature Medicine paper linking circulating erythritol to thrombosis and major adverse cardiac events. The signal is real but interpretation is contested: erythritol is also produced endogenously from glucose via the pentose phosphate pathway, so high blood erythritol may be a marker of metabolic disease rather than caused by dietary intake.
Where it lands now: well-tolerated, deeply studied, but a question mark hangs over heavy long-term use. People on healthy diets using it occasionally are likely fine; the signal applies more to those with existing cardiovascular risk factors using high doses daily.
- Best-tolerated sugar alcohol — minimal GI effect
- Zero glycemic impact
- Tooth-friendly — non-cariogenic
- 2023 cardiovascular association under investigation
- Cooling sensation on the tongue
- 70% sweetness — needs more volume than sugar
Regulatory status
In practice
- Keto baking, sugar-free chocolate
- High cardiovascular risk + heavy daily use
- Strong cooling sensation aversion
Truvia, Swerve, ChocZero, most 'keto' baked goods
The evidence
Selected peer-reviewed sources behind the score. Open access where possible. Read our scoring methodology for how we weight evidence tiers.
Recommended swaps
Higher-scoring alternatives that perform similarly in use.